Nrf2 regulation is a research area focused on understanding the mechanisms by which the nuclear factor erythroid 2-related factor 2 (Nrf2) is regulated in cells. Nrf2 is a key transcription factor that plays a critical role in protecting cells from oxidative stress and inflammation by regulating the expression of antioxidant and detoxifying genes. Research in this area aims to identify the signaling pathways and molecular mechanisms that control the activation and degradation of Nrf2, as well as the factors that influence its binding to target genes. This knowledge could potentially lead to the development of novel therapies for diseases characterized by oxidative stress and inflammation, such as cancer, neurodegenerative disorders, and autoimmune diseases.